Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01427
Species: Homo sapiens
Position : chr16:51624689-51625572
Year: 2025
Title: Range extender mediates long-distance enhancer activity
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  40604280
MONDO:
Tissue: Limb Bud
Tissue Ontology ID: UBERON:0005417
Cell Source: Zone of polarizing activity cells
CVCL ID:
Cell Type: mesenchymal cell
Cell Ontology ID: CL:0000134
Experiment Type: Enhancer activity assay, Functional perturbation assay
High Throughput Method: ChIP-seq, RNA-seq, Hi-C
Low Throughput Method: Transgenic Reporter Assay, CRISPR Knockout, CRISPR Knock-in, RT-RT-qPCR, Whole-mount in situ hybridization, Skeletal staining
About Target Gene
Target gene : SHH
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 3 found
Enhancer ID Position Tissue Cell Disease
E_01583 chr16:51623899-51624805 Embryonic Limb Bud mesenchymal cell --
E_01584 chr16:51623899-51624805 Limb Bud mesenchymal cell --
E_01426 chr16:51624689-51625572 Embryonic Limb Bud mesenchymal cell --
Expression of Target Genes for the Enhancer