About Enhancer
| Enhancer ID: | E_01451 |
| Species: | Homo sapiens |
| Position : | chr5:1320000-1322000   |
| Year: | 2021 |
| Title: | Enhancer release and retargeting activates disease-susceptibility genes |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 34040254 |
| MONDO: | |
| Tissue: | Embryonic Kidney |
| Tissue Ontology ID: | UBERON:0002113 |
| Cell Source: | 293T |
| CVCL ID: | CVCL_0063 |
| Cell Type: | embryonic kidney cell |
| Cell Ontology ID: | CL:0002139 |
| Experiment Type: | Enhancer activity assay, Functional perturbation assay, TF binding assay, Chromatin interaction assay |
| High Throughput Method: | ChIP-seq, Hi-C, ChIA-PET, RNA-seq, WGS |
| Low Throughput Method: | CRISPR Knockout, RT-RT-qPCR, 4C-seq, ChIP-RT-qPCR, Sanger Sequencing |
About Target Gene
| Target gene : | TERT |
About TF
| TF name : | CTCF |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| CTCF | Activation of anterior HOX genes in hindbrain development during early embryogenesis | reactome | 120 |
| CTCF | TGF_beta_Receptor | netpath | 220 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer