Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01460
Species: Homo sapiens
Position : chr8:128556059-128557653
Year: 2022
Title: Targeting of non-coding RNAs encoded by novel MYC enhancers inhibits the proliferation of human hepatic carcinoma cells in vitro
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Disease
Disease Name: hepatocellular carcinoma
PMID:  35039581
MONDO: MONDO:0007256
Tissue: Liver
Tissue Ontology ID: UBERON:0002107
Cell Source: HepG2
CVCL ID: CVCL_0027
Cell Type: hepatocellular carcinoma cell
Cell Ontology ID: CL:0000182
Experiment Type: Enhancer activity assay, Functional perturbation assay
High Throughput Method: ChIP-seq, GRO-seq
Low Throughput Method: Luciferase Reporter Assay, CRISPR Knockout, qRT-PCR
About Target Gene
Target gene : MYC
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 2 found
Enhancer ID Position Tissue Cell Disease
E_01708 chr8:126650000-129950000 Colon colorectal carcinoma cell colorectal carcinoma
E_01608 chr8:128556457-128556814 Liver hepatocellular carcinoma cell hepatocellular carcinoma
Expression of Target Genes for the Enhancer