About Enhancer
| Enhancer ID: | E_01460 |
| Species: | Mus musculus |
| Position : | chr17:35499359-35507923   |
| Year: | 2015 |
| Title: | Functional annotation of native enhancers with a Cas9-histone demethylase fusion. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 25775043 |
| Cell Source: | Mouse Embryonic Stem Cell |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay; Chromatin interaction assay; Endogenous enhancer perturbation; In vivo functional validation |
| High Throughput Method: | ATAC-seq |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; CRISPR-Cas9 targeted editing/deletion; ChIP-qPCR/ChIP; 3C |
About Target Gene
| Target gene : | NA |
About TF
| TF name : | Tbx3 |
About Regulatory State
| Regulatory State : | Repressed |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Tbx3 | Hs_Mesodermal_Commitment_Pathway_WP2857_87780 | wikipathways | 47 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
8 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01937 | chr17:35501113-35507015 | NA | NA | NA |
| E_01871 | chr17:35501272-35506872 | NA | NA | NA |
| E_03090 | chr17:35502632-35504632 | NA | NA | NA |
| E_03091 | chr17:35502632-35504632 | NA | NA | NA |
| E_03092 | chr17:35502632-35504632 | NA | NA | NA |
| E_03093 | chr17:35502632-35504632 | NA | NA | NA |
| E_01517 | chr17:35503912-35504118 | embryo | embryonic stem cell | NA |
| E_01523 | chr17:35504981-35505186 | embryo | embryonic stem cell | NA |
Expression of Target Genes for the Enhancer