About Enhancer
| Enhancer ID: | E_01515 |
| Species: | Mus musculus |
| Position : | chr11:112217210-112217767   |
| Year: | 2018 |
| Title: | Sex reversal following deletion of a single distal enhancer of Sox9. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 29903884 |
| Tissue: | gonad |
| Tissue Ontology ID: | UBERON:0000991 |
| Cell Source: | Testis |
| Experiment Type: | TF-binding/chromatin assay; Endogenous enhancer perturbation; In vivo functional validation |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | CRISPR-Cas9 targeted editing/deletion; ChIP-qPCR/ChIP; RT-qPCR/qPCR |
About Target Gene
| Target gene : | Sox9 |
About TF
| TF name : | Sry |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Sry | AndrogenReceptor | netpath | 167 |
| Sry | Deactivation of the beta-catenin transactivating complex | reactome | 42 |
| Sry | Regulation of Androgen receptor activity | pid | 54 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
3 found
Expression of Target Genes for the Enhancer