About Enhancer
| Enhancer ID: | E_01517 |
| Species: | Mus musculus |
| Position : | chr17:35503912-35504118   |
| Year: | 2015 |
| Title: | Functional annotation of native enhancers with a Cas9-histone demethylase fusion. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 25775043 |
| Tissue: | embryo |
| Tissue Ontology ID: | UBERON:0000922 |
| Cell Source: | mouse embryonic stem cells |
| Cell Type: | embryonic stem cell |
| Cell Ontology ID: | CL:0002322 |
| Experiment Type: | Enhancer activity assay; Epigenome-editing assay; Functional perturbation assay |
| High Throughput Method: | ATAC-seq data integration; gene-expression microarray |
| Low Throughput Method: | dCas9-LSD1 sgRNA targeting of the Pou5f1 distal enhancer; luciferase reporter assay; colony phenotype assay; RT-qPCR |
About Target Gene
| Target gene : | Pou5f1 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
7 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01460 | chr17:35499359-35507923 | NA | NA | NA |
| E_01937 | chr17:35501113-35507015 | NA | NA | NA |
| E_01871 | chr17:35501272-35506872 | NA | NA | NA |
| E_03090 | chr17:35502632-35504632 | NA | NA | NA |
| E_03091 | chr17:35502632-35504632 | NA | NA | NA |
| E_03092 | chr17:35502632-35504632 | NA | NA | NA |
| E_03093 | chr17:35502632-35504632 | NA | NA | NA |
Expression of Target Genes for the Enhancer