Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01519
Species: Homo sapiens
Position : chr9:21016991-21017491
Year: 2020
Title: A genetic variant controls interferon-?? gene expression in human myeloid cells by preventing C/EBP-?? binding on a conserved enhancer
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  33147212
MONDO:
Tissue: Blood
Tissue Ontology ID: UBERON:0000178
Cell Source: Primary monocyte-derived macrophages
CVCL ID:
Cell Type: macrophage
Cell Ontology ID: CL:0000235
Experiment Type: Enhancer activity assay, TF binding assay
High Throughput Method: Hi-C, ChIP-seq, RNA-seq
Low Throughput Method: Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR
About Target Gene
Target gene : IFNB1
About TF
TF name :
About Regulatory State
Regulatory State : Silenced
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer