About Enhancer
| Enhancer ID: | E_01534 |
| Species: | Mus musculus |
| Position : | chr4:46410632-46411247   |
| Year: | 2020 |
| Title: | Enhancer dependence of cell-type-specific gene expression increases with developmental age. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 32817427 |
| Tissue: | bone marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | Erythroblasts |
| Cell Type: | erythroblast |
| Cell Ontology ID: | CL:0000765 |
| Experiment Type: | Functional perturbation assay, Chromatin interaction assay, TF binding assay; Endogenous enhancer perturbation; TF binding assay; Chromatin interaction assay |
| High Throughput Method: | HiChIP, ChIP-seq, RNA-seq, ATAC-seq; HiChIP |
| Low Throughput Method: | CRISPR Knockout, RT-RT-qPCR; CRISPR-Cas9 endogenous deletion/editing |
About Target Gene
| Target gene : | Hemgn |
About TF
| TF name : | Gata1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Gata1 | C-MYB transcription factor network | pid | 87 |
| Gata1 | Factors involved in megakaryocyte development and platelet production | reactome | 111 |
| Gata1 | IL3 | netpath | 84 |
| Gata1 | Notch-mediated HES/HEY network | pid | 48 |
| Gata1 | p73 transcription factor network | pid | 80 |
| Gata1 | Signaling events mediated by HDAC Class I | pid | 89 |
| Gata1 | Signaling events mediated by HDAC Class II | pid | 58 |
Enhancer Associated Network
Overlapping Enhancers (mm10)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01535 | chr4:46410632-46411247 | liver | erythroid progenitor cell | NA |
Expression of Target Genes for the Enhancer