About Enhancer
| Enhancer ID: | E_01539 |
| Species: | Mus musculus |
| Position : | chr12:111517811-111518523   |
| Year: | 2020 |
| Title: | Enhancer dependence of cell-type-specific gene expression increases with developmental age. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 32817427 |
| Tissue: | blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | MEL cells |
| Cell Type: | definitive erythroblast |
| Experiment Type: | Enhancer activity assay; Functional perturbation assay; Chromatin interaction assay |
| High Throughput Method: | ATAC-seq; H3K27ac ChIP-seq; Myb ChIP-seq; Gata1 HiChIP; RNA-seq |
| Low Throughput Method: | v4C; CRISPR/Cas9 deletion; qRT-PCR |
About Target Gene
| Target gene : | Tnfaip2 |
About TF
| TF name : | Myb |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Myb | AP-1 transcription factor network | pid | 71 |
| Myb | C-MYB transcription factor network | pid | 87 |
| Myb | Factors involved in megakaryocyte development and platelet production | reactome | 111 |
| Myb | IL2 signaling events mediated by PI3K | pid | 38 |
| Myb | IL4-mediated signaling events | pid | 66 |
| Myb | Notch-mediated HES/HEY network | pid | 48 |
| Myb | Prolactin | netpath | 105 |
| Myb | Hs_Neural_Crest_Differentiation_WP2064_79263 | wikipathways | 40 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer