About Enhancer
| Enhancer ID: | E_01541 |
| Species: | Mus musculus |
| Position : | chr1:13093655-13096290   |
| Year: | 2021 |
| Title: | Enhancer-associated H3K4 methylation safeguards in vitro germline competence. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 34599190 |
| Tissue: | embryo |
| Tissue Ontology ID: | UBERON:0000922 |
| Cell Source: | ES-R1 |
| CVCL ID: | CVCL_2167 |
| Cell Type: | embryonic stem cell |
| Cell Ontology ID: | CL:0002322 |
| Experiment Type: | Enhancer chromatin-state profiling; functional enhancer deletion; germline-competence assay |
| High Throughput Method: | H3K4me1/H3K4me2/H3K4me3/H3K27ac ChIP-seq; ATAC-seq; RNA-seq; DNA methylation profiling; 4C-seq; Capture Hi-C integration; single-cell RNA-seq |
| Low Throughput Method: | CRISPR-Cas9 enhancer deletion; clonal genotyping/Sanger validation; RT-qPCR; CD15/CD61 flow cytometry |
About Target Gene
| Target gene : | Prdm14 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
6 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01852 | chr1:13041306-13127367 | NA | NA | NA |
| E_01853 | chr1:13041306-13127367 | NA | NA | NA |
| E_01854 | chr1:13041306-13127367 | NA | NA | NA |
| E_01560 | chr1:13093655-13096290 | embryo | primordial germ cell-like cell | NA |
| E_01561 | chr1:13093655-13096290 | embryo | epiblast-like cell | NA |
| E_03578 | chr1:13093655-13096290 | embryo | epiblast cell | NA |
Expression of Target Genes for the Enhancer