About Enhancer
| Enhancer ID: | E_01546 |
| Species: | Homo sapiens |
| Position : | chr7:55016139-55018139   |
| Year: | 2018 |
| Title: | E6 Protein Expressed by High-Risk HPV Activates Super-Enhancers of the EGFR and c-MET Oncogenes by Destabilizing the Histone Demethylase KDM5C |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | cervical cancer |
| PMID: | 29339538 |
| MONDO: | MONDO:0001156 |
| Tissue: | Cervix |
| Tissue Ontology ID: | UBERON:0000002 |
| Cell Source: | CaSki cell |
| CVCL ID: | CVCL_1100 |
| Cell Type: | cervical adenocarcinoma cell |
| Cell Ontology ID: | CL:0000069 |
| Experiment Type: | Enhancer functional perturbation, Chromatin interaction assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | 3C, RT-RT-qPCR |
About Target Gene
| Target gene : | EGFR |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01536 | chr7:54978916-55304142 | Breast | breast carcinoma cell | breast carcinoma |
Expression of Target Genes for the Enhancer