About Enhancer
| Enhancer ID: | E_01547 |
| Species: | Homo sapiens |
| Position : | chr13:73607397-74169928   |
| Year: | 2019 |
| Title: | Inhibition of super enhancer downregulates the expression of KLF5 in basal-like breast cancers |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | breast carcinoma |
| PMID: | 31360115 |
| MONDO: | MONDO:0006120 |
| Tissue: | Breast |
| Tissue Ontology ID: | UBERON:0000310 |
| Cell Source: | HCC1806 |
| CVCL ID: | CVCL_1258 |
| Cell Type: | breast carcinoma cell |
| Cell Ontology ID: | CL:0000646 |
| Experiment Type: | Functional perturbation assay, Enhancer activity assay, TF binding assay |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | CRISPRi, RT-RT-qPCR, Western blot, SRB Cell Viability Assay, Flow Cytometry Cell Cycle Analysis, EdU Incorporation Assay |
About Target Gene
| Target gene : | KLF5 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01548 | chr13:73607397-74169928 | Breast | breast carcinoma cell | breast carcinoma |
Expression of Target Genes for the Enhancer