Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01559
Species: Mus musculus
Position : chr1:13084831-13085465
Year: 2021
Title: Enhancer-associated H3K4 methylation safeguards in vitro germline competence.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  34599190
Tissue: embryo
Tissue Ontology ID: UBERON:0000922
Cell Source: ES-R1
CVCL ID: CVCL_2167
Cell Type: primordial germ cell-like cell
Experiment Type: Enhancer chromatin-state profiling; functional enhancer deletion; germline-competence assay
High Throughput Method: H3K4me1/H3K4me2/H3K4me3/H3K27ac ChIP-seq; ATAC-seq; RNA-seq; DNA methylation profiling; 4C-seq; Capture Hi-C integration; single-cell RNA-seq
Low Throughput Method: CRISPR-Cas9 enhancer deletion; clonal genotyping/Sanger validation; RT-qPCR; CD15/CD61 flow cytometry
About Target Gene
Target gene : Prdm14
About TF
TF name : NA
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 4 found
Enhancer ID Position Tissue Cell Disease
E_01852 chr1:13041306-13127367 NA NA NA
E_01853 chr1:13041306-13127367 NA NA NA
E_01854 chr1:13041306-13127367 NA NA NA
E_01540 chr1:13084831-13085465 embryo embryonic stem cell NA
Expression of Target Genes for the Enhancer