About Enhancer
| Enhancer ID: | E_01561 |
| Species: | Homo sapiens |
| Position : | chr3:70904000-70907000   |
| Year: | 2026 |
| Title: | Super-enhancer-driven core transcription factor FOXP1 delays endothelial cell senescence via phase separation-mediated SESN3 activation |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 41355963 |
| MONDO: | |
| Tissue: | Umbilical vein |
| Tissue Ontology ID: | UBERON:0002066 |
| Cell Source: | HUVECs |
| CVCL ID: | |
| Cell Type: | umbilical vein endothelial cell |
| Cell Ontology ID: | CL:0002615 |
| Experiment Type: | Enhancer activity assay, Functional perturbation assay |
| High Throughput Method: | CUT&Tag-seq, ATAC-seq, RNA-seq |
| Low Throughput Method: | Luciferase reporter assay, CRISPRi, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | FOXP1 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer