About Enhancer
| Enhancer ID: | E_01564 |
| Species: | Homo sapiens |
| Position : | chr20:21548504-21587972   |
| Year: | 2025 |
| Title: | p300/CBP is an essential driver of pathogenic enhancer activity and gene expression in Ewing sarcoma |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | Ewing sarcoma |
| PMID: | 40890402 |
| MONDO: | MONDO:0003368 |
| Tissue: | Bone |
| Tissue Ontology ID: | UBERON:0001474 |
| Cell Source: | A673 cells |
| CVCL ID: | CVCL_0080 |
| Cell Type: | Ewing sarcoma cell |
| Cell Ontology ID: | CL:0000050 |
| Experiment Type: | Enhancer activity assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | CRISPR knockout, ChIP-RT-qPCR, RT-RT-qPCR |
About Target Gene
| Target gene : | NKX2-2 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer