About Enhancer
| Enhancer ID: | E_01565 |
| Species: | Homo sapiens |
| Position : | chr11:10200000-10205000   |
| Year: | 2025 |
| Title: | Super-enhancer-hijacking RBBP7 potentiates metastasis and stemness of breast cancer via recruiting NuRD complex subunit LSD1 |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | breast carcinoma |
| PMID: | 40038738 |
| MONDO: | MONDO:0006120 |
| Tissue: | Breast |
| Tissue Ontology ID: | UBERON:0000310 |
| Cell Source: | MCF-7 cells |
| CVCL ID: | CVCL_0031 |
| Cell Type: | breast carcinoma cell |
| Cell Ontology ID: | CL:0000646 |
| Experiment Type: | Super-enhancer activity assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | CRISPR knockout, ChIP-RT-qPCR, RT-RT-qPCR |
About Target Gene
| Target gene : | SOX2 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer