Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01571
Species: Mus musculus
Position : chr12:111517811-111518523
Year: 2020
Title: Enhancer dependence of cell-type-specific gene expression increases with developmental age.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Normal
PMID:  32817427
Tissue Ontology ID: UBERON:0002371
Cell Source: Erythroblasts
Cell Ontology ID: CL:0000765
Experiment Type: Functional perturbation assay; Chromatin interaction assay; TF binding assay
High Throughput Method: HiChIP; ChIP-seq; RNA-seq; ATAC-seq
Low Throughput Method: qRT-PCR
About Target Gene
Target gene : Tnfaip2
About TF
TF name : Gata1
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Gata1 C-MYB transcription factor network pid 87
Gata1 Factors involved in megakaryocyte development and platelet production reactome 111
Gata1 IL3 netpath 84
Gata1 Notch-mediated HES/HEY network pid 48
Gata1 p73 transcription factor network pid 80
Gata1 Signaling events mediated by HDAC Class I pid 89
Gata1 Signaling events mediated by HDAC Class II pid 58
Enhancer Associated Network
Overlapping Enhancers (mm10) 2 found
Enhancer ID Position Tissue Cell Disease
E_01538 chr12:111517811-111518523 blood definitive erythroblast NA
E_01539 chr12:111517811-111518523 blood definitive erythroblast NA
Expression of Target Genes for the Enhancer