About Enhancer
| Enhancer ID: | E_01580 |
| Species: | Homo sapiens |
| Position : | chr11:76586431-76600121   |
| Year: | 2020 |
| Title: | A distal enhancer at risk locus 11q135 promotes suppression of colitis by Treg cells |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 32499651 |
| MONDO: | |
| Tissue: | Colon |
| Tissue Ontology ID: | UBERON:0001155 |
| Cell Source: | Primary Treg cells |
| CVCL ID: | |
| Cell Type: | regulatory T cell |
| Cell Ontology ID: | CL:0000815 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq, HiChIP, hQTL, eQTL |
| Low Throughput Method: | CRISPRa, ChIP-RT-qPCR, RT-RT-qPCR, Flow Cytometry |
About Target Gene
| Target gene : | LRRC32 |
About TF
| TF name : | STAT5 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer