Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01581
Species: Mus musculus
Position : chr16:25400000-25900000
Year: 2020
Title: ERG orchestrates chromatin interactions to drive prostate cell fate reprogramming.
Genome Build: mm10
Enhancer Type: Enhancer
Condition: Disease
Disease Name: prostate cancer
PMID:  32701507
MONDO: MONDO:0008315
Tissue: prostate gland
Tissue Ontology ID: UBERON:0002367
Cell Source: Mouse Prostate Epithelial Organoids
Cell Type: mouse prostate epithelial organoid cell
Experiment Type: Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay
High Throughput Method: ChIP-seq; RNA-seq; Hi-C; ATAC-seq
Low Throughput Method: CRISPR Knockout, qRT-PCR; Western blot; Immunofluorescence
About Target Gene
Target gene : Trp63
About TF
TF name : NA
About Regulatory State
Regulatory State : Repressed
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm10) 1 found
Enhancer ID Position Tissue Cell Disease
E_01526 chr16:25574210-25575090 prostate gland prostate epithelial cell NA
Expression of Target Genes for the Enhancer