About Enhancer
| Enhancer ID: | E_01582 |
| Species: | Homo sapiens |
| Position : | chr16:51623658-51623898   |
| Year: | 2025 |
| Title: | Range extender mediates long-distance enhancer activity |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 40604280 |
| MONDO: | |
| Tissue: | Limb Bud |
| Tissue Ontology ID: | UBERON:0005417 |
| Cell Source: | Zone of polarizing activity cells |
| CVCL ID: | |
| Cell Type: | mesenchymal cell |
| Cell Ontology ID: | CL:0000134 |
| Experiment Type: | TF binding assay, Enhancer activity assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | Transgenic Reporter Assay, CRISPR Knockout, CRISPR Knock-in, RT-RT-qPCR, Whole-mount in situ hybridization, Skeletal staining, EMSA |
About Target Gene
| Target gene : | SHH |
About TF
| TF name : | LHX2; LHX9; LEF1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Expression of Target Genes for the Enhancer