Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01598
Species: Homo sapiens
Position : chr14:24527672-24527672
Year: 2025
Title: Genetic coupling of enhancer activity and connectivity in gene expression control
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  39870618
MONDO:
Tissue: Blood
Tissue Ontology ID: UBERON:0000178
Cell Source: Primary CD14+ monocytes
CVCL ID:
Cell Type: CD14-positive monocyte
Cell Ontology ID: CL:0001053
Experiment Type: Chromatin interaction assay, TF binding assay
High Throughput Method: Capture Hi-C, ATAC-seq, RNA-seq, ChIP-seq (CTCF), 4C-seq
Low Throughput Method: qRT-PCR, and ChIP-qPCR
About Target Gene
Target gene : PCK2
About TF
TF name : CTCF
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
CTCF Activation of anterior HOX genes in hindbrain development during early embryogenesis reactome 120
CTCF TGF_beta_Receptor netpath 220
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer