Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01601
Species: Homo sapiens
Position : chr8:127330655-127330840
Year: 2023
Title: Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma
Genome Build: hg38
Enhancer Type: Super-enhancer
Condition: Disease
Disease Name: medulloblastoma
PMID:  37945900
MONDO: MONDO:0005146
Tissue: Brain
Tissue Ontology ID: UBERON:0000955
Cell Source: D458
CVCL ID: CVCL_1160
Cell Type: medulloblastoma cell
Cell Ontology ID: CL:0000127
Experiment Type: Enhancer activity assay, Functional perturbation assay, Chromatin interaction assay
High Throughput Method: Hi-C, ATAC-seq, RNA-seq
Low Throughput Method: CRISPRi, qRT-PCR, FISH
About Target Gene
Target gene : MYC
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 2 found
Enhancer ID Position Tissue Cell Disease
E_01708 chr8:126650000-129950000 Colon colorectal carcinoma cell colorectal carcinoma
E_01602 chr8:127330840-127330927 Brain medulloblastoma cell medulloblastoma
Expression of Target Genes for the Enhancer