About Enhancer
| Enhancer ID: | E_01633 |
| Species: | Homo sapiens |
| Position : | chr11:102245603-102246344   |
| Year: | 2023 |
| Title: | BRD7 inhibits enhancer activity and expression of BIRC2 to suppress tumor growth and metastasis in nasopharyngeal carcinoma |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | nasopharyngeal carcinoma |
| PMID: | 36788209 |
| MONDO: | MONDO:0005350 |
| Tissue: | Nasopharynx |
| Tissue Ontology ID: | UBERON:0008338 |
| Cell Source: | 5-8F |
| CVCL ID: | CVCL_6846 |
| Cell Type: | nasopharyngeal carcinoma cell |
| Cell Ontology ID: | CL:0000069 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | BIRC2 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01634 | chr11:102245603-102246344 | Nasopharynx | nasopharyngeal carcinoma cell | nasopharyngeal carcinoma |
Expression of Target Genes for the Enhancer