About Enhancer
| Enhancer ID: | E_01642 |
| Species: | Homo sapiens |
| Position : | chr11:5225000-5226000   |
| Year: | 2022 |
| Title: | Systematic comparison of CRISPR-based transcriptional activators uncovers gene-regulatory features of enhancer-promoter interactions |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | chronic myeloid leukemia |
| PMID: | 35849129 |
| MONDO: | MONDO:0011998 |
| Tissue: | Blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | K562 |
| CVCL ID: | CVCL_0004 |
| Cell Type: | chronic myeloid leukemia cell |
| Cell Ontology ID: | CL:0001054 |
| Experiment Type: | Functional perturbation assay |
| High Throughput Method: | CUT&RUN |
| Low Throughput Method: | CRISPR Knockout, CRISPRi, RT-RT-qPCR, 3C-RT-qPCR, Western blot |
About Target Gene
| Target gene : | HBG1 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
4 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01640 | chr11:5225000-5226000 | Embryonic Kidney | embryonic kidney cell | -- |
| E_01641 | chr11:5225000-5226000 | Cervix | cervical adenocarcinoma cell | cervical cancer |
| E_01643 | chr11:5225000-5226000 | Bone | osteosarcoma cell | osteosarcoma |
| E_01808 | chr11:5225440-5225500 | Bone Marrow | hematopoietic stem cell | -- |
Expression of Target Genes for the Enhancer