About Enhancer
| Enhancer ID: | E_01645 |
| Species: | Homo sapiens |
| Position : | chr2:11000000-11002000   |
| Year: | 2024 |
| Title: | Engrailed-1 promotes pancreatic cancer metastasis |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | pancreatic ductal adenocarcinoma |
| PMID: | 38110836 |
| MONDO: | MONDO:0005147 |
| Tissue: | Pancreas |
| Tissue Ontology ID: | UBERON:0001264 |
| Cell Source: | CFPAC1 |
| CVCL ID: | CVCL_0019 |
| Cell Type: | pancreatic ductal adenocarcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Enhancer activity assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR |
About Target Gene
| Target gene : | EN1 |
About TF
| TF name : | EN1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| EN1 | Hs_Dopaminergic_Neurogenesis_WP2855_87239 | wikipathways | 19 |
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer