About Enhancer
| Enhancer ID: | E_01652 |
| Species: | Homo sapiens |
| Position : | chr18:59350000-59950000   |
| Year: | 2021 |
| Title: | Epigenomic landscape and 3D genome structure in pediatric high-grade glioma |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | glioblastoma |
| PMID: | 34078608 |
| MONDO: | MONDO:0005142 |
| Tissue: | Pons |
| Tissue Ontology ID: | UBERON:0000988 |
| Cell Source: | Human glioblastoma cell |
| CVCL ID: | |
| Cell Type: | glioblastoma cell |
| Cell Ontology ID: | CL:0000127 |
| Experiment Type: | Chromatin interaction assay, Enhancer activity assay |
| High Throughput Method: | Hi-C, ChIP-seq, RNA-seq |
| Low Throughput Method: | RT-RT-qPCR |
About Target Gene
| Target gene : | CCBE1 |
About TF
| TF name : | FOSL2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| FOSL2 | AP-1 transcription factor network | pid | 71 |
| FOSL2 | Gene expression of IL2 by AP-1 ( CD4 T cell receptor signaling (JNK cascade) ) | inoh | 5 |
| FOSL2 | Gene expression of IL2 by AP-1 ( CD4 T cell receptor signaling ) | inoh | 5 |
| FOSL2 | JNK cascade ( CD4 T cell receptor signaling (JNK cascade) ) | inoh | 12 |
| FOSL2 | JNK cascade ( CD4 T cell receptor signaling ) | inoh | 10 |
| FOSL2 | Validated transcriptional targets of AP1 family members Fra1 and Fra2 | pid | 37 |
| FOSL2 | Validated transcriptional targets of deltaNp63 isoforms | pid | 47 |
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer