Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01661
Species: Homo sapiens
Position : chr20:54119731-54198946
Year: 2024
Title: MYC activity at enhancers drives prognostic transcriptional programs through an epigenetic switch
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Disease
Disease Name: breast carcinoma
PMID:  38454021
MONDO: MONDO:0006120
Tissue: Breast
Tissue Ontology ID: UBERON:0000310
Cell Source: MCF7 (ER+)
CVCL ID: CVCL_0031
Cell Type: breast carcinoma cell
Cell Ontology ID: CL:0000646
Experiment Type: TF binding assay, Functional perturbation assay
High Throughput Method: ChIP-seq, RNA-seq
Low Throughput Method: Fulvestrant treatment, RT-RT-qPCR
About Target Gene
Target gene : CYP24A1
About TF
TF name : MYC; ESR1
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer