Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01662
Species: Homo sapiens
Position : chr1:39000000-39645000
Year: 2023
Title: Enhancer remodeling activates NOTCH3 signaling to confer chemoresistance in advanced nasopharyngeal carcinoma
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Disease
Disease Name: nasopharyngeal carcinoma
PMID:  37563118
MONDO: MONDO:0005350
Tissue: Nasopharynx
Tissue Ontology ID: UBERON:0001714
Cell Source: CNE-2
CVCL ID: CVCL_6889
Cell Type: nasopharyngeal carcinoma cell
Cell Ontology ID: CL:0000069
Experiment Type: Enhancer activity assay, Functional perturbation assay
High Throughput Method: ChIP-seq, RNA-seq
Low Throughput Method: ChIP-RT-qPCR, RT-RT-qPCR, Western blot
About Target Gene
Target gene : HEYL
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer