Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01666
Species: Homo sapiens
Position : chr5:1230131-1337133
Year: 2025
Title: HBV sequence integrated to enhancer acting as oncogenic driver epigenetically promotes hepatocellular carcinoma development
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Disease
Disease Name: hepatocellular carcinoma
PMID:  40405227
MONDO: MONDO:0007256
Tissue: Liver
Tissue Ontology ID: UBERON:0002107
Cell Source: Huh7
CVCL ID: CVCL_0336
Cell Type: hepatocellular carcinoma cell
Cell Ontology ID: CL:0000182
Experiment Type: Enhancer activity assay, Functional perturbation assay
High Throughput Method: ChIP-seq, RNA-seq
Low Throughput Method: ChIP-RT-qPCR, RT-RT-qPCR
About Target Gene
Target gene : TERT
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 5 found
Enhancer ID Position Tissue Cell Disease
E_01593 chr5:1230131-1231631 Brain excitatory neuron --
E_01711 chr5:1230260-1230530 Brain excitatory neuron --
E_01632 chr5:1294000-1297400 Liver hepatocellular carcinoma cell hepatocellular carcinoma
E_01319 chr5:1320000-1322000 Embryonic Kidney embryonic kidney cell --
E_01451 chr5:1320000-1322000 Embryonic Kidney embryonic kidney cell --
Expression of Target Genes for the Enhancer