Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01682
Species: Mus musculus
Position : chr11:112482190-112483273
Year: 2024
Title: Chromatin profiling identifies chondrocyte-specific Sox9 enhancers important for skeletal development.
Genome Build: mm9
Enhancer Type: Enhancer
Condition: Normal
PMID:  38855864
Tissue: embryo
Tissue Ontology ID: UBERON:0000922
Cell Source: C3H/10T1/2 clone 8
CVCL ID: CVCL_0190
Cell Type: fibroblast
Cell Ontology ID: CL:0000057
Experiment Type: Enhancer activity assay; Endogenous enhancer perturbation; In vivo functional validation
Low Throughput Method: Luciferase Reporter Assay; RT-qPCR; Western blot; CRISPR-Cas9 endogenous deletion/editing; Mouse genetic deletion/knock-in
About Target Gene
Target gene : Sox9
About TF
TF name : Pitx1
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (mm9) 2 found
Enhancer ID Position Tissue Cell Disease
E_01604 chr11:112482190-112483273 cartilage tissue chondrocyte NA
E_01689 chr11:112482190-112483273 NA chondrogenic cell NA
Expression of Target Genes for the Enhancer