Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01686
Species: Homo sapiens
Position : chr16:54926631-54929466
Year: 2024
Title: Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Disease
Disease Name: T-cell acute lymphoblastic leukemia
PMID:  39316719
MONDO: MONDO:0004947
Tissue: Blood
Tissue Ontology ID: UBERON:0000178
Cell Source: T-ALL cells
CVCL ID:
Cell Type: T lymphoblast
Cell Ontology ID: CL:0002419
Experiment Type: Chromatin conformation capture, Histone modification ChIP-sequencing
High Throughput Method: UMI-4C, H3K27ac HiChIP, H3K27ac ChIP-seq
Low Throughput Method: qRT-PCR, and ChIP-qPCR
About Target Gene
Target gene : H3K27AC
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer