Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01692
Species: Homo sapiens
Position : chr19:11090422-11091028
Year: 2026
Title: Functional interrogation of candidate cis-regulatory elements at the LDLR locus
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Disease
Disease Name: hepatocellular carcinoma
PMID:  41843552
MONDO: MONDO:0007256
Tissue: Liver
Tissue Ontology ID: UBERON:0002107
Cell Source: HuH7 cells
CVCL ID: CVCL_0336
Cell Type: hepatocellular carcinoma cell
Cell Ontology ID: CL:0000182
Experiment Type: Functional perturbation assay
High Throughput Method: CRISPR screen
Low Throughput Method: CRISPR knockout, CRISPRi, RT-RT-qPCR
About Target Gene
Target gene : LDLR
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 2 found
Enhancer ID Position Tissue Cell Disease
E_01805 chr19:11090150-11090715 Tongue tongue squamous cell carcinoma cell tongue squamous cell carcinoma
E_01750 chr19:11090550-11090678 Liver hepatocellular carcinoma cell hepatocellular carcinoma
Expression of Target Genes for the Enhancer