About Enhancer
| Enhancer ID: | E_01708 |
| Species: | Homo sapiens |
| Position : | chr8:126650000-129950000   |
| Year: | 2023 |
| Title: | The Mediator complex regulates enhancer-promoter interactions |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | colorectal carcinoma |
| PMID: | 37430065 |
| MONDO: | MONDO:0005132 |
| Tissue: | Colon |
| Tissue Ontology ID: | UBERON:0001155 |
| Cell Source: | Human colorectal carcinoma cell |
| CVCL ID: | |
| Cell Type: | colorectal carcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | Capture-C, Micro-Capture-C, Tiled-MCC, ChIP-seq, CUT&Tag, ATAC-seq, TT-seq |
| Low Throughput Method: | Western blot |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
24 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01657 | chr8:126800000-126900000 | Kidney | malignant rhabdoid tumor cell | malignant rhabdoid tumor |
| E_01636 | chr8:127247000-127248000 | Pancreas | pancreatic ductal adenocarcinoma cell | pancreatic ductal adenocarcinoma |
| E_01637 | chr8:127247000-127248000 | Pancreas | pancreatic ductal adenocarcinoma cell | pancreatic ductal adenocarcinoma |
| E_01601 | chr8:127330655-127330840 | Brain | medulloblastoma cell | medulloblastoma |
| E_01602 | chr8:127330840-127330927 | Brain | medulloblastoma cell | medulloblastoma |
| E_01603 | chr8:127330927-127331000 | Brain | medulloblastoma cell | medulloblastoma |
| E_01888 | chr8:127661390-127661641 | Skin | fibroblast | -- |
| E_01390 | chr8:127668529-127669329 | Breast | breast carcinoma cell | breast carcinoma |
| E_01897 | chr8:127675276-128081453 | Prostate | prostate carcinoma cell | prostate cancer |
| E_01465 | chr8:127750000-127752000 | Breast | breast carcinoma cell | breast carcinoma |
| E_01650 | chr8:127750000-127752000 | Breast | breast carcinoma cell | breast carcinoma |
| E_01694 | chr8:128041672-128043891 | Bone Marrow | hematopoietic stem cell | -- |
| E_01460 | chr8:128556059-128557653 | Liver | hepatocellular carcinoma cell | hepatocellular carcinoma |
| E_01608 | chr8:128556457-128556814 | Liver | hepatocellular carcinoma cell | hepatocellular carcinoma |
| E_01924 | chr8:128600697-128601159 | Cervix | cervical adenocarcinoma cell | cervical cancer |
| E_01648 | chr8:128740000-128750000 | Blood | chronic myeloid leukemia cell | chronic myeloid leukemia |
| E_01307 | chr8:128747000-128748000 | Blood | chronic myeloid leukemia cell | chronic myeloid leukemia |
| E_01847 | chr8:128747000-128748000 | Colon | colorectal carcinoma cell | colorectal carcinoma |
| E_01306 | chr8:128804981-128806980 | Colon | colorectal carcinoma cell | colorectal carcinoma |
| E_01295 | chr8:128805000-128807000 | Colon | colorectal carcinoma cell | colorectal carcinoma |
| E_01658 | chr8:128840000-128890000 | Kidney | malignant rhabdoid tumor cell | malignant rhabdoid tumor |
| E_00137 | chr8:128900000-128900620 | Bone marrow | multiple myeloma cell line | Multiple myeloma |
| E_00138 | chr8:128900000-128900620 | Bone marrow | multiple myeloma cell line | Multiple myeloma |
| E_01659 | chr8:129440000-129740000 | Kidney | malignant rhabdoid tumor cell | malignant rhabdoid tumor |
Expression of Target Genes for the Enhancer