About Enhancer
| Enhancer ID: | E_01714 |
| Species: | Mus musculus |
| Position : | chr1:92390990-92393985   |
| Year: | 2024 |
| Title: | Spatial enhancer activation influences inhibitory neuron identity during mouse embryonic development. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 38528203 |
| Tissue: | forebrain |
| Tissue Ontology ID: | UBERON:0001890 |
| Cell Source: | Mouse embryonic GE progenitor |
| Cell Type: | neural progenitor cell |
| Cell Ontology ID: | CL:0011020 |
| Experiment Type: | Enhancer activity assay; TF binding assay; Endogenous enhancer perturbation; Chromatin-state profiling; In vivo functional validation |
| High Throughput Method: | ChIP-seq |
| Low Throughput Method: | Transgenic reporter assay; ChIP; Site-directed/motif mutagenesis; In vivo phenotyping |
About Target Gene
| Target gene : | Prox1 |
About TF
| TF name : | Dlx5 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Dlx5 | Validated transcriptional targets of deltaNp63 isoforms | pid | 47 |
| Dlx5 | Hs_MECP2_and_Associated_Rett_Syndrome_WP3584_91190 | wikipathways | 12 |
| Dlx5 | Hs_Neural_Crest_Differentiation_WP2064_79263 | wikipathways | 40 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer