About Enhancer
| Enhancer ID: | E_01754 |
| Species: | Homo sapiens |
| Position : | chrY:2792658-2792907   |
| Year: | 2024 |
| Title: | A conserved NR5A1-responsive enhancer regulates SRY in testis-determination |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 38555298 |
| MONDO: | |
| Tissue: | Testis |
| Tissue Ontology ID: | UBERON:0000473 |
| Cell Source: | hiPSC-derived Sertoli-like cells |
| CVCL ID: | |
| Cell Type: | Sertoli cell |
| Cell Ontology ID: | CL:0000216 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Functional perturbation assay |
| High Throughput Method: | Whole Genome Sequencing, RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay, RT-RT-qPCR, Western blot, Sanger Sequencing |
About Target Gene
| Target gene : | SRY |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Silenced |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01755 | chrY:2792658-2792907 | Embryonic Kidney | embryonic kidney cell | -- |
Expression of Target Genes for the Enhancer