About Enhancer
| Enhancer ID: | E_01757 |
| Species: | Mus musculus |
| Position : | chr8:106610150-106612150   |
| Year: | 2015 |
| Title: | Enhancer cooperativity as a novel mechanism underlying the transcriptional regulation of E-cadherin during mesenchymal to epithelial transition. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 25652130 |
| Cell Source: | Non-tumorigenic Mouse Mammary Gland Cells |
| Experiment Type: | Enhancer activity assay; TF-binding/chromatin assay; Chromatin interaction assay |
| Low Throughput Method: | Luciferase reporter assay; Reporter assay; ChIP-qPCR/ChIP; 3C; RT-qPCR/qPCR |
About Target Gene
| Target gene : | Cdh1 |
About TF
| TF name : | Hnf4a |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| Hnf4a | FOXA2 and FOXA3 transcription factor networks | pid | 45 |
| Hnf4a | HIF-1-alpha transcription factor network | pid | 67 |
| Hnf4a | Nuclear Receptor transcription pathway | reactome | 51 |
| Hnf4a | Regulation of gene expression in beta cells | reactome | 17 |
| Hnf4a | Regulation of nuclear SMAD2/3 signaling | pid | 82 |
| Hnf4a | TGF_beta_Receptor | netpath | 220 |
| Hnf4a | Maturity onset diabetes of the young | kegg | 25 |
Enhancer Associated Network
Expression of Target Genes for the Enhancer