About Enhancer
| Enhancer ID: | E_01760 |
| Species: | Mus musculus |
| Position : | chr11:111838889-111839334   |
| Year: | 2018 |
| Title: | Combinatorial CRISPR/Cas9 Approach to Elucidate a Far-Upstream Enhancer Complex for Tissue-Specific Sox9 Expression. |
| Genome Build: | mm10 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| PMID: | 30146478 |
| Tissue: | cartilage tissue |
| Tissue Ontology ID: | UBERON:0002418 |
| Cell Source: | enhancer-deletion mouse |
| Cell Type: | chondrocyte |
| Cell Ontology ID: | CL:0000138 |
| Experiment Type: | Same defined cartilage enhancer retained as independent deletion-model evidence row; Endogenous enhancer perturbation |
| High Throughput Method: | Promoter-enhancer complex NGS |
| Low Throughput Method: | CRISPR/Cas9 enhancer-deletion mouse; skeletal phenotyping; RT-qPCR; CRISPR-Cas9 endogenous deletion/editing |
About Target Gene
| Target gene : | Sox9 |
About TF
| TF name : | NA |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (mm10)
5 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01704 | chr11:111838889-111839334 | NA | NA | NA |
| E_01713 | chr11:111838889-111839334 | cartilage tissue | chondrocyte | NA |
| E_01731 | chr11:111838889-111839334 | cartilage tissue | chondrocyte | NA |
| E_01741 | chr11:111838889-111839334 | cartilage tissue | chondrocyte | NA |
| E_01758 | chr11:111838889-111839334 | cartilage tissue | chondrocyte | NA |
Expression of Target Genes for the Enhancer