Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01777
Species: Homo sapiens
Position : chr14:24058261-24058761
Year: 2025
Title: Genetic coupling of enhancer activity and connectivity in gene expression control
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Disease
Disease Name: glioblastoma
PMID:  39870618
MONDO: MONDO:0005142
Tissue: Brain
Tissue Ontology ID: UBERON:0000955
Cell Source: U373MG
CVCL ID: CVCL_2219
Cell Type: glioblastoma cell
Cell Ontology ID: CL:0000127
Experiment Type: Chromatin interaction assay, TF binding assay
High Throughput Method: ATAC-seq, Capture Hi-C
Low Throughput Method: ChIP-RT-qPCR, 4C-seq
About Target Gene
Target gene : PCK2
About TF
TF name : CTCF
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
CTCF Activation of anterior HOX genes in hindbrain development during early embryogenesis reactome 120
CTCF TGF_beta_Receptor netpath 220
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer