About Enhancer
| Enhancer ID: | E_01784 |
| Species: | Homo sapiens |
| Position : | chr5:69232027-69234027   |
| Year: | 2020 |
| Title: | Targeting Super-Enhancer-Associated Oncogenes in Osteosarcoma with THZ2, a Covalent CDK7 Inhibitor |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | chronic myeloid leukemia |
| PMID: | 31937612 |
| MONDO: | MONDO:0011998 |
| Tissue: | Bone marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | Leukemia cell lines |
| CVCL ID: | |
| Cell Type: | chronic myeloid leukemia cell |
| Cell Ontology ID: | CL:0001054 |
| Experiment Type: | Super-enhancer targeting therapy study, Chromatin interaction assay |
| High Throughput Method: | |
| Low Throughput Method: | 3C, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | CDK7 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer