About Enhancer
| Enhancer ID: | E_01807 |
| Species: | Homo sapiens |
| Position : | chr3:185824281-185824602   |
| Year: | 2024 |
| Title: | KLF7 regulates super-enhancer-driven IGF2BP2 overexpression to promote the progression of head and neck squamous cell carcinoma |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 38443991 |
| MONDO: | |
| Tissue: | Bone Marrow |
| Tissue Ontology ID: | UBERON:0002371 |
| Cell Source: | CD34+ hematopoietic stem/progenitor cells |
| CVCL ID: | |
| Cell Type: | hematopoietic stem cell |
| Cell Ontology ID: | CL:0001029 |
| Experiment Type: | Enhancer activity assay, TF binding assay |
| High Throughput Method: | |
| Low Throughput Method: | Luciferase Reporter Assay, ChIP-RT-qPCR, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | IGF2BP2 |
About TF
| TF name : | KLF7 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| KLF7 | Hs_Cytokines_and_Inflammatory_Response_WP530_79331 | wikipathways | 21 |
Enhancer Associated Network
Overlapping Enhancers (hg38)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01806 | chr3:185824281-185824602 | Tongue | tongue squamous cell carcinoma cell | tongue squamous cell carcinoma |
Expression of Target Genes for the Enhancer