About Enhancer
| Enhancer ID: | E_01833 |
| Species: | Homo sapiens |
| Position : | chr1:116506181-116506381   |
| Year: | 2024 |
| Title: | rs10924104 in the expression enhancer motif of CD58 confers susceptibility to human autoimmune diseases |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 37994973 |
| MONDO: | |
| Tissue: | Bronchus |
| Tissue Ontology ID: | UBERON:0002037 |
| Cell Source: | HBEC3-KT |
| CVCL ID: | |
| Cell Type: | bronchial epithelial cell |
| Cell Ontology ID: | CL:0002591 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | Hi-C |
| Low Throughput Method: | Luciferase Reporter Assay, CRISPR Knockout, ChIP-RT-qPCR, EMSA, RT-RT-qPCR |
About Target Gene
| Target gene : | CD58 |
About TF
| TF name : | ZNF35 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01832 | chr1:116506181-116506381 | Blood | acute monocytic leukemia cell | acute monocytic leukemia |
Expression of Target Genes for the Enhancer