About Enhancer
| Enhancer ID: | E_01834 |
| Species: | Homo sapiens |
| Position : | chr17:39611085-39689899   |
| Year: | 2024 |
| Title: | Mechanism of ERBB2 gene overexpression by the formation of super-enhancer with genomic structural abnormalities in lung adenocarcinoma without clinically actionable genetic alterations |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 38862995 |
| MONDO: | |
| Tissue: | Bronchus |
| Tissue Ontology ID: | UBERON:0002037 |
| Cell Source: | HSAEC1-KT |
| CVCL ID: | |
| Cell Type: | bronchial epithelial cell |
| Cell Ontology ID: | CL:0002591 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, WGS, Hi-C, RNA-seq |
| Low Throughput Method: | CRISPR Knockout, RT-RT-qPCR, FACS, Western blot |
About Target Gene
| Target gene : | ERBB2 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01835 | chr17:39611085-39689899 | Liver | hepatocellular carcinoma cell | hepatocellular carcinoma |
Expression of Target Genes for the Enhancer