About Enhancer
| Enhancer ID: | E_01835 |
| Species: | Homo sapiens |
| Position : | chr17:39611085-39689899   |
| Year: | 2024 |
| Title: | Mechanism of ERBB2 gene overexpression by the formation of super-enhancer with genomic structural abnormalities in lung adenocarcinoma without clinically actionable genetic alterations |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | hepatocellular carcinoma |
| PMID: | 38862995 |
| MONDO: | MONDO:0007256 |
| Tissue: | Liver |
| Tissue Ontology ID: | UBERON:0002107 |
| Cell Source: | HepG2 |
| CVCL ID: | CVCL_0027 |
| Cell Type: | hepatocellular carcinoma cell |
| Cell Ontology ID: | CL:0000182 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | ChIP-seq, WGS, Hi-C, RNA-seq |
| Low Throughput Method: | CRISPR Knockout, RT-RT-qPCR, FACS, Western blot |
About Target Gene
| Target gene : | ERBB2 |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01834 | chr17:39611085-39689899 | Bronchus | bronchial epithelial cell | -- |
Expression of Target Genes for the Enhancer