Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01851
Species: Homo sapiens
Position : chr17:66452427-66453982
Year: 2023
Title: The ABL-MYC axis controls WIPI1-enhanced autophagy in lifespan extension
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  37620393
MONDO:
Tissue: Embryonic Kidney
Tissue Ontology ID: UBERON:0002113
Cell Source: HEK293
CVCL ID: CVCL_0045
Cell Type: embryonic kidney cell
Cell Ontology ID: CL:0002139
Experiment Type: Enhancer activity assay, TF binding assay
High Throughput Method: RNA-seq
Low Throughput Method: Luciferase Reporter Assay, ChIP-RT-qPCR, qRT-PCR, Western blot
About Target Gene
Target gene : WIPI1
About TF
TF name : MYC; MAX
About Regulatory State
Regulatory State : Silenced
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer