About Enhancer
| Enhancer ID: | E_01854 |
| Species: | Homo sapiens |
| Position : | chr17:48005000-48010000   |
| Year: | 2024 |
| Title: | CDK5RAP3 is a novel super-enhancer-driven gene activated by master TFs and regulates ER-Phagy in neuroblastoma |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | prostate cancer |
| PMID: | 38636893 |
| MONDO: | MONDO:0008315 |
| Tissue: | Prostate |
| Tissue Ontology ID: | UBERON:0002367 |
| Cell Source: | LuCaP PDX |
| CVCL ID: | |
| Cell Type: | patient-derived xenograft prostate carcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Enhancer activity assay, TF binding assay |
| High Throughput Method: | ChIP-seq, CUT&Tag, RNA-seq |
| Low Throughput Method: | Luciferase Reporter Assay, CUT&RUN-RT-qPCR, RT-RT-qPCR, Western blot |
About Target Gene
| Target gene : | CDK5RAP3 |
About TF
| TF name : | MEIS2; HAND2 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01376 | chr17:47940000-48020000 | Adrenal gland | neuroblastoma cell | neuroblastoma |
Expression of Target Genes for the Enhancer