About Enhancer
| Enhancer ID: | E_01888 |
| Species: | Homo sapiens |
| Position : | chr8:127661390-127661641   |
| Year: | 2020 |
| Title: | A rare variant of African ancestry activates 8q24 lncRNA hub by modulating cancer associated enhancer |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Normal |
| Disease Name: | -- |
| PMID: | 32680982 |
| MONDO: | |
| Tissue: | Skin |
| Tissue Ontology ID: | UBERON:0000014 |
| Cell Source: | Human neonatal foreskin fibroblasts |
| CVCL ID: | |
| Cell Type: | fibroblast |
| Cell Ontology ID: | CL:0000057 |
| Experiment Type: | Enhancer activity assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | |
| Low Throughput Method: | Luciferase Reporter Assay, 4C, CRISPRi, RT-qPCR |
About Target Gene
| Target gene : | MYC |
About TF
| TF name : |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
1 found
| Enhancer ID | Position | Tissue | Cell | Disease |
|---|---|---|---|---|
| E_01708 | chr8:126650000-129950000 | Colon | colorectal carcinoma cell | colorectal carcinoma |
Expression of Target Genes for the Enhancer