Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01889
Species: Homo sapiens
Position : chr17:44542500-44543500
Year: 2025
Title: Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  40997217
MONDO:
Tissue: Skin
Tissue Ontology ID: UBERON:0000014
Cell Source: Human neonatal foreskin fibroblasts
CVCL ID:
Cell Type: fibroblast
Cell Ontology ID: CL:0000057
Experiment Type: CRISPR interference-based functional screen
High Throughput Method: ATAC-seq, RNA-seq, HiCAR, CRISPRi screening, single-cell RNA-seq
Low Throughput Method: Luciferase reporter assay, RT-qPCR, flow cytometry
About Target Gene
Target gene : FZD2
About TF
TF name :
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer