About Enhancer
| Enhancer ID: | E_01905 |
| Species: | Homo sapiens |
| Position : | chr16:15600300-15601300   |
| Year: | 2014 |
| Title: | Aberrant TAL1 activation is mediated by an interchromosomal interaction in human T-cell acute lymphoblastic leukemia |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | prostate cancer |
| PMID: | 23698277 |
| MONDO: | MONDO:0008315 |
| Tissue: | Prostate |
| Tissue Ontology ID: | UBERON:0002367 |
| Cell Source: | VCaP |
| CVCL ID: | CVCL_2235 |
| Cell Type: | prostate carcinoma cell |
| Cell Ontology ID: | CL:0000066 |
| Experiment Type: | Enhancer activity assay, TF binding assay, Chromatin interaction assay, Functional perturbation assay |
| High Throughput Method: | 4C-seq, ChIP-seq |
| Low Throughput Method: | Luciferase reporter assay, ChIP-RT-qPCR, 3C, RT-RT-qPCR, shRNA knockdown, Western blot |
About Target Gene
| Target gene : | TAL1 |
About TF
| TF name : | MAF |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|---|---|---|
| MAF | AP-1 transcription factor network | pid | 71 |
| MAF | C-MYB transcription factor network | pid | 87 |
| MAF | Calcineurin-regulated NFAT-dependent transcription in lymphocytes | pid | 50 |
| MAF | Kaposi sarcoma-associated herpesvirus | mirtarbase | 13 |
| MAF | Hs_TYROBP_Causal_Network_WP3945_90843 | wikipathways | 54 |
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer