About Enhancer
| Enhancer ID: | E_01914 |
| Species: | Homo sapiens |
| Position : | chr11:120233455-120235455   |
| Year: | 2015 |
| Title: | POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer |
| Genome Build: | hg38 |
| Enhancer Type: | Enhancer |
| Condition: | Disease |
| Disease Name: | T-cell acute lymphoblastic leukemia |
| PMID: | 29945888 |
| MONDO: | MONDO:0004947 |
| Tissue: | Blood |
| Tissue Ontology ID: | UBERON:0000178 |
| Cell Source: | Jurkat human CD4+ T leukemia cell line |
| CVCL ID: | CVCL_0065 |
| Cell Type: | T lymphoblast |
| Cell Ontology ID: | CL:0002419 |
| Experiment Type: | Enhancer activity assay, TF binding assay |
| High Throughput Method: | ChIP-seq, RNA-seq |
| Low Throughput Method: | 3C, FISH, Immunofluorescence, RT-PCR, Western blot, RT-RT-qPCR |
About Target Gene
| Target gene : | POU2F3 |
About TF
| TF name : | POU2F3; ASCL1; NEUROD1; INSM1 |
About Regulatory State
| Regulatory State : | Active |
Upstream Pathway Annotation of TF
| GeneName | Pathway Name | Source | Gene Number |
|---|
Enhancer Associated Network
Overlapping Enhancers (hg38)
No overlapping enhancers found in hg38 at this locus.
Expression of Target Genes for the Enhancer