Enhancer Detail

Comprehensive information about experimentally validated enhancers

About Enhancer
Enhancer ID: E_01953
Species: Homo sapiens
Position : chr7:155754267-155755366
Year: 2008
Title: Regulation of a remote Shh forebrain enhancer by the Six3 homeoprotein
Genome Build: hg38
Enhancer Type: Enhancer
Condition: Normal
Disease Name: --
PMID:  18836447
MONDO:
Tissue: Forebrain
Tissue Ontology ID: UBERON:0001890
Cell Source: Primary embryonic cells
CVCL ID:
Cell Type: embryonic cell
Cell Ontology ID: CL:0000000
Experiment Type: Enhancer activity assay, TF binding assay, Functional perturbation assay
High Throughput Method:
Low Throughput Method: Transgenic Reporter Assay, ChIP-RT-qPCR, EMSA, RT-RT-qPCR
About Target Gene
Target gene : SHH
About TF
TF name : SIX3
About Regulatory State
Regulatory State : Active
Upstream Pathway Annotation of TF
GeneName Pathway Name Source Gene Number
Enhancer Associated Network
Overlapping Enhancers (hg38) 1 found
Enhancer ID Position Tissue Cell Disease
E_01954 chr7:155754267-155755366 Inner cell mass embryonic stem cell --
Expression of Target Genes for the Enhancer